姓名 刘建柱
职称：教授
办公室电话：0538-8242478
刘建柱，博士，教授，博士生导师、博士后合作导师。中共威尼斯人在线赌场-赌场app 党委委员，教授委员会委员，兽医专业学位点点长、中华人民共和国执业兽医师出题、审题专家，第六、七届中国兽药典委员会委员，全国专业标准化技术委员会委员，全国畜禽质量标准创新中心专家，山东省优秀本科、硕士、博士学位论文指导教师。曾任动物科技学院临床兽医学系系主任，山东农业大学动物保健医院院长。主编《动物临床诊断学》等国家级规划教材6部，主编《宠物医师临床急救手册》（执业兽医师培训教材）等科普图书19本，先后主持国家自然基金，山东省自然基金，“十三五”重点研发计划项目、农业部行业专项子课题、归国留学基金项目、博士后特别资助等项目20余项。现已在 Journal of Hazardous Materials，Biosens Bioelectron，Emerging Microbes & Infections，Biomed Pharmacother，Chemosphere， Carbohydr Polym. Human & Experimental Toxicology，Vaccine、Veterinary Parasitol，Research in Veterinary science，等期刊杂志上发表研究性论文240余篇，其中SCI收录论文110余篇。
教育经历
1995-1999 黑龙江八一农垦大学 动物科技学院 本科 农学学士（兽医学）
2000-2003 黑龙江八一农垦大学 动物科技学院 硕士 农学硕士（预防兽医学）
2003-2006 韩国 忠南大学 兽医学院 博士 兽医学博士（临床兽医学-小动物内科学）
工作经历
2024.3-至今 山东农业大学 威尼斯人在线赌场 教授 博士生导师
2014-2024.3 山东农业大学 动物科技学院 教授 博士生导师
2006-2014 山东农业大学 动物科技学院 副教授 硕士生导师
1999-2000 黑龙江省海林市畜牧局 检疫员
荣誉奖励
国家优秀自费留学生奖学金获得者 , 2005
执教课程
兽医临床诊断学，动物临床诊断学，特种经济动物疾病学，宠物观赏与管理（本科生）
现代兽医临床诊疗技术，现代动物内科与诊断学，兽医学进展（硕士、博士研究生）
研究领域
本实验室主要研究领域：
1. 临床微生物学
2. 动物营养代谢病与中毒病
3. 小动物疾病学
承担的科研项目
1、国家自然基金，Parkin在Cr（VI）致鸡肝细胞线粒体自噬中的调控及机制研,31872535。
2、山东省自然基金，基于ATF6介导Cr(VI)致DF1细胞凋亡的调控机制研究，ZR201709250352，
3、“十三五”重点研发计划，犬猫心电图诊断及心电监护技术与规程研究，2016YFD0501007。
4、“十三五”重点研发计划，镉、铬、砷等重金属在畜禽机体上危害与残留特征及其防控技术研究，2016YFD0501208。
5、山东省青年科学家奖励基金，猪附红细胞体MSG1基因人工定点诱变及对其抗原性的影响，BS2009NY007。
6、2、山东省自然基金，MTF-1 靶向IREB2 调控 Cr(VI)致鸡肾小管上皮细胞铁死亡的作用机制、 ZR2024MC079。
7、横向课题：调控“肠-肝”循环的枯草芽孢杆菌的开发232091
8、横向课题：桃树叶及其提取物产品的开发、242189
教研项目
1）兽医专业学位研究生创新实践能力培养模式研究，山东省教育厅,研究生教育创新重点项目，2021年11月，山东农业大学，主持人：刘建柱。
2）全日制兽医硕士专业学位研究生培养模式的研究，山东省教育厅,研究生教育创新项目，2013 年 8 月，山东农业大学，主持人：刘建柱。
3）兽医专业研究生应用型人才培养模式的研究与实践，山东省教育厅，研究生教育创新项目，2015 年 10 月，山东农业大学，主持人：刘建柱。
4）教学案例库在兽医专业学位研究生培养中的作用研究，山东省教育厅, 研究生教育创新项目，2017 年 1 月，山东农业大学，主持人：刘建柱。
5）兽医临床现代诊疗技术教学案例库建设，山东省教育厅，案例库课程建设项目，2018年1月，山东农业大学，主持人：刘建柱。
6）山东省教育教学研究课题，《动物临床诊断学》慕课课程建设与探讨，2015年6 月。主持人：刘建柱。
7）山东农业大学慕课建设项目，《动物临床诊断学》，2014年9月。主持人：刘建柱。
8）山东农业大学研究生课程建设项目，《兽医临床现代诊疗技术》，2016 年 3 月。主持人：刘建柱。
发表文章和出版图书教材
一．论文
1.Xu H, Wang S, Wang X, Zhang P, Zheng Q, Qi C, Liu X, Li M, Liu Y, Liu J.JRole of Rab GTPases in Bacteria Escaping from Vesicle Trafficking of Host Cells. Microbiol. 2024 Aug;62(8):581-590. doi: 10.1007/s12275-024-00162-9. Epub 2024 Aug 30.PMID: 39212865 Review.
2.Liu X, Dong W, Zhang Y, Tian Y, Xiao Y, Yang M, Yuan X, Li G, Liu J, Kai M.In vitro and in vivo evaluation of antibacterial activity and mechanism of luteolin from Humulus scandens against Escherichia coli from chicken.Poult Sci. 2024 Nov;103(11):104132. doi: 10.1016/j.psj.2024.104132. Epub 2024 Aug 6.PMID: 39208485
3.Yan G, Wang S, Cui Y, Xue K, Liu Y, Liu J.Bacterial Diversity and Antimicrobial Resistance of Microorganisms Isolated from Teat Cup Liners in Dairy Farms in Shandong Province, China.Animals (Basel). 2024 Jul 25;14(15):2167. doi: 10.3390/ani14152167.PMID: 39123692
4.Development and evaluation of a triplex droplet digital PCR method for differentiation of M. tuberculosis, M. bovis and BCG.Qu Y, Liu M, Sun X, Liu Y, Liu J, Hu L, Jiang Z, Qi F, Nan W, Yan X, Sun M, Shao W, Li J, Sun S, Zhang H, Fan X.Front Microbiol. 2024 Jun 14;15:1397792. doi: 10.3389/fmicb.2024.1397792. eCollection 2024.PMID: 38946908
5.Xu H, Wang X, Zhang Z, Hu J, Yu Y, Wang J, Liu Y, Liu J.Staphylococcus aureus promotes its intracellular survival by inhibiting Rab11-Rab11FIP4-mediated vesicle trafficking.Vet Microbiol. 2024 Jun;293:110091. doi: 10.1016/j.vetmic.2024.110091. Epub 2024 Apr 12.PMID: 38626624
6.Song K, Liu X, Xu H, Li M, Zheng Q, Qi C, Wang X, Liu Y, Zheng P, Liu J.Cr(VI) induces ferroptosis in DF-1 cells by simultaneously perturbing iron homeostasis of ferritinophagy and mitophagy.Sci Total Environ. 2024 May 15;925:171818. doi: 10.1016/j.scitotenv.2024.171818. Epub 2024 Mar 19.PMID: 38508245
7.Guo X, Zhao X, Li L, Jiang M, Zhou A, Gao Y, Zheng P, Liu J, Zhao X.Platycodon grandiflorus polysaccharide inhibits the inflammatory response of 3D4/21 cells infected with PCV2.Microb Pathog. 2024 Apr;189:106592. doi: 10.1016/j.micpath.2024.106592. Epub 2024 Feb 28.PMID: 38423406
8.Cui Y, Song K, Liu X, Xu H, Wang X, Cheng G, Zheng P, Liu J.Research on Bacterial Diversity and Antibiotic Resistance in the Dairy Farm Environment in a Part of Shandong Province.Animals (Basel). 2024 Jan 3;14(1):160. doi: 10.3390/ani14010160.PMID: 38200891
9.Cui Y, Zhang P, Song K, Qi C, Liu Y, Liu J.Role of PERK-Mediated Endoplasmic Reticulum Stress in Ferroptosis Caused by Hexavalent Chromium in Chicken Hepatocytes.Biol Trace Elem Res. 2024 Nov;202(11):5208-5218. doi: 10.1007/s12011-023-04046-8. Epub 2024 Jan 6.PMID: 38183555
10.Qi C, Lv C, Jiang M, Zhao X, Gao Y, Wang Y, Zhang P, Liu J, Zhao X.The surface morphology of Atractylodes macrocephala polysaccharide and its inhibitory effect on PCV2 replication.J Sci Food Agric. 2024 Apr;104(6):3624-3636. doi: 10.1002/jsfa.13246. Epub 2024 Feb 12.PMID: 38148571
11.Li Z, Song K, Du Y, Zhang Z, Fan R, Zheng P, Liu J. Diagnosis of a Rabbit Hemorrhagic Disease Virus 2 (RHDV2) and the Humoral Immune Protection Effect of VP60 Vaccine.Curr Issues Mol Biol. 2023 Aug 8;45(8):6605-6617. doi: 10.3390/cimb45080417.PMID: 37623236
12.Cai D, Tian B, Liu Y, Rehman MU, Ranucci D, Veronesi F, Varcasia A, Jia W, Liu J.The seroprevalence of canine dirofilariosis in dogs in the eastern coastal areas of China.Heliyon. 2023 Jun 7;9(6):e17009. doi: 10.1016/j.heliyon.2023.e17009. eCollection 2023 Jun.PMID: 37484229
13.Xing Y, Cui Y, Xu G, Qi C, Zhang M, Cheng G, Liu Y, Liu J.Protective effect of Platycodon grandiflorus polysaccharide on apoptosis and mitochondrial damage induced by pseudorabies virus in PK-15 cells.Cell Biochem Biophys. 2023 Sep;81(3):493-502. doi: 10.1007/s12013-023-01141-4. Epub 2023 Jun 13.PMID: 37310618
14.Wang X, Li H, Wang J, Xu H, Xue K, Liu X, Zhang Z, Liu J, Liu Y.Staphylococcus aureus extracellular vesicles induce apoptosis and restrain mitophagy-mediated degradation of damaged mitochondria.Microbiol Res. 2023 Aug;273:127421. doi: 10.1016/j.micres.2023.127421. Epub 2023 May 30.PMID: 37267814
15.Zhu Y, Song K, Cheng G, Xu H, Wang X, Qi C, Zhang P, Liu Y, Liu J.Changes in the bacterial communities in chromium-contaminated soils.Front Vet Sci. 2023 Jan 4;9:1066048. doi: 10.3389/fvets.2022.1066048. eCollection 2022.PMID: 36686195
16.Zhang Z, Zheng P, Qi C, Cui Y, Qi Y, Xue K, Yan G, Liu J.Platycodon grandiflorus Polysaccharides Alleviate Cr(VI)-Induced Apoptosis in DF-1 Cells via ROS-Drp1 Signal Pathway.Life (Basel). 2022 Dec 19;12(12):2144. doi: 10.3390/life12122144.PMID: 36556509
17.Wang L, Zheng P, Cui Y, Zhang Z, Song K, Liu Y, Liu J.Regulation of Parkin in Cr (VI)-induced mitophagy in chicken hepatocytes.Ecotoxicol Environ Saf. 2022 Dec 15;248:114315. doi: 10.1016/j.ecoenv.2022.114315. Epub 2022 Nov 21.PMID: 36423368
18.Zhao X, Liu Y, Wang H, Li W, Liu J.Editorial: Xenophagy: Its role in pathogen infections.Front Cell Infect Microbiol. 2022 Aug 26;12:1003451. doi: 10.3389/fcimb.2022.1003451. eCollection 2022.PMID: 36093208
19.Li Z, Hu J, Wang X, Du Y, Yin J, Gao J, Han B, Cui S, Liu Y, Liu J.Effects of Artemisinin on Escherichia coli-Induced Mastitis in Bovine Mammary Epithelial Cells and Mice.Vet Sci. 2022 Jul 26;9(8):381. doi: 10.3390/vetsci9080381.PMID: 35893774
20.Guo S, Qi M, Li H, Cui Y, Qi C, Cheng G, Lv M, Zheng P, Liu J.The Protective Effect of Lycium Ruthenicum Murr Anthocyanins in Cr (VI)-Induced Mitophagy in DF-1 Cells.Life (Basel). 2022 Jul 25;12(8):1115. doi: 10.3390/life12081115.PMID: 35892917
21.Li L, Chen X, Lv M, Cheng Z, Liu F, Wang Y, Zhou A, Liu J, Zhao X.Effect of Platycodon grandiflorus Polysaccharide on M1 Polarization Induced by Autophagy Degradation of SOCS1/2 Proteins in 3D4/21 Cells.Front Immunol. 2022 Jun 30;13:934084. doi: 10.3389/fimmu.2022.934084. eCollection 2022.PMID: 35844489
22.Lu C, Wang Q, Jiang Y, Zhang M, Meng X, Li Y, Liu B, Yin Z, Liu H, Peng C, Li F, Yue Y, Hao M, Sui Y, Wang L, Cheng G, Liu J, Chu Z, Zhu C, Dong H, Ding X.J Discovery of a novel nucleoside immune signaling molecule 2'-deoxyguanosine in microbes and plants.Adv Res. 2023 Apr;46:1-15. doi: 10.1016/j.jare.2022.06.014. Epub 2022 Jul 8.PMID: 35811061
23.Zhang H, Chang YF, Liu J.Editorial: Regulation of Mitochondrial Function on Animal Diseases.Front Vet Sci. 2022 Jun 17;9:943860. doi: 10.3389/fvets.2022.943860. eCollection 2022.PMID: 35782556
24.Geng N, Gao X, Wang X, Cui S, Wang J, Liu Y, Chen W, Liu J.Hydrogen helps to ameliorate Staphylococcus aureus-induced mastitis in mice.Int Immunopharmacol. 2022 Aug;109:108940. doi: 10.1016/j.intimp.2022.108940. Epub 2022 Jun 11.PMID: 35700582
25.Cheng G, Zhang S, Lv M, Qi C, Fan R, Guo X, Liu J, Zhao X.The surface morphology of Platycodon grandiflorus polysaccharide and its anti-apoptotic effect by targeting autophagy.Phytomedicine. 2022 Aug;103:154212. doi: 10.1016/j.phymed.2022.154212. Epub 2022 May 27.PMID: 35665615
26.Wang Y, Qin X, Diao X, Liu Y, Liu J.Serological survey for antibodies to Encephalitozoon cuniculi and Toxoplasma gondii in pet rabbits in eastern coastal areas of China.J Vet Med Sci. 2022 Jun 10;84(6):777-783. doi: 10.1292/jvms.21-0660. Epub 2022 Apr 29.PMID: 35491103
27.Qi M, Geng H, Geng N, Cui Y, Qi C, Cheng G, Song K, Hu L, Liu Y, Liu J, Han B.Streptococcus agalactiae-induced autophagy of bovine mammary epithelial cell via PI3K/AKT/mTOR pathway.J Dairy Res. 2022 Apr 7:1-7. doi: 10.1017/S0022029922000243. Online ahead of print.PMID: 35388773
28. Wang X, Liu M, Geng N, Du Y, Li Z, Gao X, Han B, Liu J, LiuY.Staphylococcus aureus mediates pyroptosis in bovine mammary epithelial cell via activation of NLRP3 inflammasome.Vet Res. 2022 Feb 5;53(1):10. doi: 10.1186/s13567-022-01027-y.PMID: 35123552
29. Wang C, Qi C, Liu M, Wang L, Cheng G, Li L, Xing Y, Zhao X, Liu J.Protective effects of agrimonolide on hypoxia-induced H9c2 cell injury by maintaining mitochondrial homeostasis.J Cell Biochem. 2021 Nov 1. doi: 10.1002/jcb.30169. Online ahead of print.PMID: 34724244
30.Wang R, Zhang W, Wang L, Geng N, Wang X, Zhang M, Liu J, Liu Y, Han B. Intracellular Staphylococcus aureus inhibits autophagy of bovine mammary epithelial cells through activating p38α.J Dairy Res. 2021 Aug;88(3):293-301. doi: 10.1017/S0022029921000649.PMID: 34425921
31. Xing Y, Wang L, Xu G, Guo S, Zhang M, Cheng G, Liu Y, Liu J. Platycodon grandiflorus polysaccharides inhibit Pseudorabies virus replication via downregulating virus-induced autophagy.Res Vet Sci. 2021 Nov;140:18-25. doi: 10.1016/j.rvsc.2021.08.004. Epub 2021 Aug 8.PMID: 34391058
32.Zou X, Jiang S, Zhang M, Hu H, Wu X, Liu J, Jin M, Cheng H.Effects of Bacillus subtilis on Production Performance, Bone Physiological Property, and Hematology Indexes in Laying Hens.Animals (Basel). 2021 Jul 8;11(7):2041. doi: 10.3390/ani11072041.PMID: 34359169
33.Liu K, Cui Y, Li H, Qi C, Cheng G, Gao X, Zhang Z, Liu Y, Liu J. Hydrogen-Rich Medium Regulates Cr(VI)-Induced ER Stress and Autophagy Signaling in DF-1 Cells.Biol Trace Elem Res. 2021 Jul 30. doi: 10.1007/s12011-021-02850-8. Online ahead of print.PMID: 34327609
34.Wang Y, Wang L, Wang X, Cheng G, Xing Y, Zhang M, Zhang P, Liu J.Inflammatory Injury and Mitophagy in the Cock Heart Induced by the Oral Administration of Hexavalent Chromium.Biol Trace Elem Res. 2022 Mar;200(3):1312-1320. doi: 10.1007/s12011-021-02715-0. Epub 2021 Apr 13.PMID: 33851329
35.Guo S, Wang X, Wang L, Cheng G, Zhang M, Xing Y, Zhao X, Liu Y, Liu J.Inflammatory injury and mitophagy of the brain in chicken exposed to Cr(VI).Environ Sci Pollut Res Int. 2021 Aug;28(31):42353-42361. doi: 10.1007/s11356-021-13675-2. Epub 2021 Apr 4.PMID: 33813707
36.Zhu Y, Wang L, Yu X, Jiang S, Wang X, Xing Y, Guo S, Liu Y, Liu J.Cr(VI) promotes tight joint and oxidative damage by activating the Nrf2/ROS/Notch1 axis.Environ Toxicol Pharmacol. 2021 Jul;85:103640. doi: 10.1016/j.etap.2021.103640. Epub 2021 Mar 20.PMID: 33757840
37.Tian B, Cai D, Li W, Bu Q, Wang M, Ye G, Liu J, Wang Y, Gou L, Yi J, Zuo Z. Identification and genotyping of a new subtype of bovine viral diarrhea virus 1 isolated from cattle with diarrhea.Arch Virol. 2021 Apr;166(4):1259-1262. doi: 10.1007/s00705-021-04990-7. Epub 2021 Feb 13.PMID: 33582856
38.Wang X, Su F, Yu X, Geng N, Li L, Wang R, Zhang M, Liu J, Liu Y, HanB. RNA-Seq Whole Transcriptome Analysis of Bovine Mammary Epithelial Cells in Response to Intracellular Staphylococcus aureus.Front Vet Sci. 2020 Dec 7;7:642. doi: 10.3389/fvets.2020.00642. eCollection 2020.PMID: 33426011
39.Zhang S, Zhao X, Hao J, Zhu Y, Wang Y, Wang L, Guo S, Yi H, Liu Y, Liu J.The role of ATF6 in Cr(VI)-induced apoptosis in DF-1 cells.J Hazard Mater. 2021 May 15;410:124607. doi: 10.1016/j.jhazmat.2020.124607. Epub 2020 Nov 19.PMID: 33243643
40. Hao J, Song Y, Tian B, Qi C, Li L, Wang L, Xing Y, Zhao X, Liu J.Platycodon grandifloras polysaccharides inhibit mitophagy injury induced by Cr (VI) in DF-1 cells.Ecotoxicol Environ Saf. 2020 Oct 1;202:110901. doi: 10.1016/j.ecoenv.2020.110901. Epub 2020 Jun 25.PMID: 32593805
41.Zhang P, Wang AP, Yang HP, Ai L, Zhang HJ, Wang YM, Bi YL, Fan HH, Gao J, Zhang HY, Liu JZ.Apelin-13 attenuates high glucose-induced calcification of MOVAS cells by regulating MAPKs and PI3K/AKT pathways and ROS-mediated signals.Biomed Pharmacother. 2020 Aug;128:110271. doi: 10.1016/j.biopha.2020.110271. Epub 2020 May 22.PMID: 32450527
42.Wang Y, Wang X, Wang L, Cheng G, Zhang M, Xing Y, Zhao X, Liu Y, Liu J. Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).Biol Trace Elem Res. 2021 Feb;199(2):703-711. doi: 10.1007/s12011-020-02176-x. Epub 2020 May 21.PMID: 32440992
43.Geng N, Wang X, Yu X, Wang R, Zhu Y, Zhang M, Liu J, Liu Y.Staphylococcus aureus Avoids Autophagy Clearance of Bovine Mammary Epithelial Cells by Impairing Lysosomal Function.Front Immunol. 2020 May 5;11:746. doi: 10.3389/fimmu.2020.00746. eCollection 2020.PMID: 32431700
44. Wang Y, Hao J, Zhang S, Li L, Wang R, Zhu Y, Liu Y, Liu J.Inflammatory injury and mitophagy induced by Cr(VI) in chicken liver.Environ Sci Pollut Res Int. 2020 Jun;27(18):22980-22988. doi: 10.1007/s11356-020-08544-3. Epub 2020 Apr 23.PMID: 32329004
45. Xu Y, Wang X, Geng N, Zhu Y, Zhang S, Liu Y, Liu J.Mitophagy is involved in chromium (VI)-induced mitochondria damage in DF-1 cells.Ecotoxicol Environ Saf. 2020 May;194:110414. doi: 10.1016/j.ecoenv.2020.110414. Epub 2020 Mar 6.PMID: 32151870
45.Geng N, Liu K, Lu J, Xu Y, Wang X, Wang R, Liu J, Liu Y, Han B.Autophagy of bovine mammary epithelial cell induced by intracellular Staphylococcus aureus.J Microbiol. 2020 Apr;58(4):320-329. doi: 10.1007/s12275-020-9182-8. Epub 2020 Feb 26.PMID: 32103442
47.Wang S, Geng N, Zhou D, Qu Y, Shi M, Xu Y, Liu K, Liu Y, Liu J.Oral Immunization of Chickens With Recombinant Lactobacillus plantarum Vaccine Against Early ALV-J Infection.Front Immunol. 2019 Oct 2;10:2299. doi: 10.3389/fimmu.2019.02299. eCollection 2019.PMID: 31632395
48.Wang C, Cheng G, Yang S, Li L, Zhang Y, Zhao X, Liu J.Protective effects of Platycodon grandiflorus polysaccharides against apoptosis induced by carbonyl cyanide 3-chlorophenylhydrazone in 3D4/21 cells.Int J Biol Macromol. 2019 Dec 1;141:1220-1227. doi: 10.1016/j.ijbiomac.2019.09.086. Epub 2019 Sep 12.PMID: 31521659
49.Lu J, Liu K, Qi M, Geng H, Hao J, Wang R, Zhao X, Liu Y, Liu J. Effects of Cr(VI) exposure on electrocardiogram, myocardial enzyme parameters, inflammatory factors, oxidative kinase, and ATPase of the heart in Chinese rural dogs.Environ Sci Pollut Res Int. 2019 Oct;26(29):30444-30451. doi: 10.1007/s11356-019-06253-0. Epub 2019 Aug 22.PMID: 31440970
50.Liu K, Chen P, Lu J, Zhu Y, Xu Y, Liu Y, Liu J.Protective Effect of Purple Tomato Anthocyanidin on Chromium(VI)-Induced Autophagy in LMH Cells by Inhibiting Endoplasmic Reticulum Stress.Biol Trace Elem Res. 2020 Apr;194(2):570-580. doi: 10.1007/s12011-019-01795-3. Epub 2019 Jul 1.PMID: 31264128
51.Cheng J, Xu Y, Zhou D, Liu K, Geng N, Lu J, Liu Y, Liu J.Novel carbon quantum dots can serve as an excellent adjuvant for the gp85 protein vaccine against avian leukosis virus subgroup J in chickens.Poult Sci. 2019 Nov 1;98(11):5315-5320. doi: 10.3382/ps/pez313.PMID: 31198967
52.Zhu Y, Xu G, Chen P, Liu K, Xu Y, Liu Y, Liu J. Effects of Cr(VI)-induced calcium-sensing receptor activation on DF-1 cell pyroptosis.Ecotoxicol Environ Saf. 2019 Sep 15;179:257-264. doi: 10.1016/j.ecoenv.2019.04.084. Epub 2019 May 1.PMID: 31054379
53.Chen P, Geng N, Zhou D, Zhu Y, Xu Y, Liu K, Liu Y, Liu J.The regulatory role of COX-2 in the interaction between Cr(VI)-induced endoplasmic reticulum stress and autophagy in DF-1 cells.Ecotoxicol Environ Saf. 2019 Apr 15;170:112-119. doi: 10.1016/j.ecoenv.2018.11.120. Epub 2018 Dec 4.PMID: 30529609
54.Xie N, Geng N, Zhou D, Xu Y, Liu K, Liu Y, Liu J.Protective effects of anthocyanin against apoptosis and oxidative stress induced by arsanilic acid in DF-1 cells.Mol Biol Rep. 2019 Feb;46(1):301-308. doi: 10.1007/s11033-018-4472-5. Epub 2018 Nov 28.PMID: 30488373
55.Li G, Niu X, Yuan S, Liang L, Liu Y, Hu L, Liu J, Cheng Z. Emergence of Morganella morganii subsp. morganii in dairy calves, China.Emerg Microbes Infect. 2018 Oct 24;7(1):172. doi: 10.1038/s41426-018-0173-3.PMID: 30353002
56. Fan W, Xu Y, Zhang P, Chen P, Zhu Y, Cheng Z, Zhao X, Liu Y, Liu J.Analysis of molecular evolution of nucleocapsid protein in Newcastle disease virus.Oncotarget. 2017 Sep 28;8(57):97127-97136. doi: 10.18632/oncotarget.21373. eCollection 2017 Nov 14.PMID: 29228598
57.Zhao X, Wang Y, Yan P, Cheng G, Wang C, Geng N, Wang X, Liu J.Effects of Polysaccharides from Platycodon grandiflorum on Immunity-Enhancing Activity In Vitro. Molecules. 2017 Nov 7;22(11):1918. doi: 10.3390/molecules22111918.PMID: 29112148
58.Fan W, Zheng P, Wang Y, Hao P, Liu J, Zhao X.Analysis of immunostimulatory activity of polysaccharide extracted from Yu-Ping-Feng in vitro and in vivo.Biomed Pharmacother. 2017 Sep;93:146-155. doi: 10.1016/j.biopha.2017.05.138. Epub 2017 Jun 17.PMID: 28628831
59.Zhu Y, Chen P, Wan H, Wang Y, Hao P, Liu Y, Liu J.Selenium-Chromium(VI) Interaction Regulates the Contents and Correlations of Trace Elements in Chicken Brain and Serum.Biol Trace Elem Res. 2018 Jan;181(1):154-163. doi: 10.1007/s12011-017-1038-7. Epub 2017 May 10.PMID: 28493199
60.Chen P, Zhu Y, Wan H, Wang Y, Hao P, Cheng Z, Liu Y, Liu J.Effects of the Oral Administration of K2Cr2O7 and Na2SeO3 on Ca, Mg, Mn, Fe, Cu, and Zn Contents in the Heart, Liver, Spleen, and Kidney of Chickens.Biol Trace Elem Res. 2017 Dec;180(2):285-296. doi: 10.1007/s12011-017-0999-x. Epub 2017 Mar 28.PMID: 28353138
61.Wang Y, Liu Y, Wan H, Zhu Y, Chen P, Hao P, Cheng Z, Liu J.Moderate selenium dosing inhibited chromium (VI) toxicity in chicken liver.J Biochem Mol Toxicol. 2017 Aug;31(8). doi: 10.1002/jbt.21916. Epub 2017 Mar 21.PMID: 28321998
62.Wan H, Zhu Y, Chen P, Wang Y, Hao P, Cheng Z, Liu Y, Liu J.Effect of various selenium doses on chromium(IV)-induced nephrotoxicity in a male chicken model.Chemosphere. 2017 May;174:306-314. doi: 10.1016/j.chemosphere.2017.01.143. Epub 2017 Jan 31.PMID: 28183056
63.Zheng P, Fan W, Wang S, Hao P, Wang Y, Wan H, Hao Z, Liu J, Zhao X. Characterization of polysaccharides extracted from Platycodon grandiflorus (Jacq.) A.DC. affecting activation of chicken peritoneal macrophages.Int J Biol Macromol. 2017 Mar;96:775-785. doi: 10.1016/j.ijbiomac.2016.12.077. Epub 2017 Jan 2.PMID: 28057573
64.Hao P, Zhu Y, Wang S, Wan H, Chen P, Wang Y, Cheng Z, Liu Y, Liu J.Selenium Administration Alleviates Toxicity of Chromium(VI) in the Chicken Brain.Biol Trace Elem Res. 2017 Jul;178(1):127-135. doi: 10.1007/s12011-016-0915-9. Epub 2016 Dec 24.PMID: 28013456
65.Fan W, Wang Y, Wang S, Cheng Z, Guo H, Zhao X, Liu J. Virulence in Newcastle disease virus: A genotyping and molecular evolution spectrum perspective.Res Vet Sci. 2017 Apr;111:49-54. doi: 10.1016/j.rvsc.2016.12.001. Epub 2016 Dec 7.PMID: 27951521
66.Cheng J, Wen S, Wang S, Hao P, Cheng Z, Liu Y, Zhao P, Liu J.gp85 protein vaccine adjuvanted with silica nanoparticles against ALV-J in chickens.Vaccine. 2017 Jan 5;35(2):293-298. doi: 10.1016/j.vaccine.2016.11.077. Epub 2016 Nov 29.PMID: 27912987
67. Liu Y, Hao P, Zhang X, Zhao X, Liu Y, Liu J.Effects of Excess Cr3+ on Trace Element Contents in the Brain and Serum in Chicken.Biol Trace Elem Res. 2017 May;177(1):180-186. doi: 10.1007/s12011-016-0875-0. Epub 2016 Oct 19.PMID: 27761845
68.Fan W, Zhang S, Hao P, Zheng P, Liu J, Zhao X.Structure characterization of three polysaccharides and a comparative study of their immunomodulatory activities on chicken macrophage.Carbohydr Polym. 2016 Nov 20;153:631-640. doi: 10.1016/j.carbpol.2016.07.116. Epub 2016 Jul 28.PMID: 27561535
69.Ma T, Liu Y, Cheng J, Liu Y, Fan W, Cheng Z, Niu X, Liu J.Liposomes containing recombinant E protein vaccine against duck Tembusu virus in ducks.Vaccine. 2016 Apr 27;34(19):2157-63. doi: 10.1016/j.vaccine.2016.03.030. Epub 2016 Mar 23.PMID: 27016654
70.The immune adjuvant response of polysaccharides from Atractylodis macrocephalae Koidz in chickens vaccinated against Newcastle disease (ND).Zhao X, Sun W, Zhang S, Meng G, Qi C, Fan W, Wang Y, Liu J.Carbohydr Polym. 2016 May 5;141:190-6. doi: 10.1016/j.carbpol.2016.01.013. Epub 2016 Jan 12.PMID: 26877012
71.Cheng J, Fan W, Zhao X, Liu Y, Cheng Z, Liu Y, Liu J.Oxidative Stress and Histological Alterations of Chicken Brain Induced by Oral Administration of Chromium(III).Biol Trace Elem Res. 2016 Sep;173(1):185-93. doi: 10.1007/s12011-016-0640-4. Epub 2016 Feb 12.PMID: 26873037
72.Hou M, Zhou D, Li G, Guo H, Liu J, Wang G, Zheng Q, Cheng Z.Identification of a variant antigenic neutralizing epitope in hypervariable region 1 of avian leukosis virus subgroup J.Vaccine. 2016 Mar 8;34(11):1399-404. doi: 10.1016/j.vaccine.2016.01.039. Epub 2016 Feb 2.PMID: 26850757
73.Liu Y, Zhao X, Zhang X, Zhao X, Liu Y, Liu J.Effects of Oral Administration of CrCl3 on the Contents of Ca, Mg, Mn, Fe, Cu, and Zn in the Liver, Kidney, and Heart of Chicken.Biol Trace Elem Res. 2016 Jun;171(2):459-467. doi: 10.1007/s12011-015-0559-1. Epub 2015 Nov 5.PMID: 26537118 Clinical Trial.
74.Meng K, Sun W, Cheng Z, Guo H, Liu J, Chai T.First detection of severe fever with thrombocytopenia syndrome virus in the tick species Haemaphysalis concinna in Shandong Province, China.Parasitol Res. 2015 Dec;114(12):4703-7. doi: 10.1007/s00436-015-4718-2. Epub 2015 Sep 8.PMID: 26350381
75.Wang Y, He J, Yang W, Muhantay G, Chen Y, Xing J, Liu J.Correlation between Heart-type Fatty Acid-binding Protein Gene Polymorphism and mRNA Expression with Intramuscular Fat in Baicheng-oil Chicken.Asian-Australas J Anim Sci. 2015 Oct;28(10):1380-7. doi: 10.5713/ajas.14.0886.PMID: 26323394 Free PMC article.
76.Liu Y, Liu C, Cheng J, Fan W, Zhang X, Liu J.Growth performance and oxidative damage in kidney induced by oral administration of Cr(III) in chicken.Chemosphere. 2015 Nov;139:365-71. doi: 10.1016/j.chemosphere.2015.07.032. Epub 2015 Jul 24.PMID: 26207879
77.Yan Z, Fan R, Yin S, Zhao X, Liu J, Li L, Zhang W, Ge L.Protective effects of Ginkgo biloba leaf polysaccharide on nonalcoholic fatty liver disease and its mechanisms.Int J Biol Macromol. 2015 Sep;80:573-80. doi: 10.1016/j.ijbiomac.2015.05.054. Epub 2015 Jun 3.PMID: 26047899
78.Sun W, Meng K, Qi C, Yang X, Wang Y, Fan W, Yan Z, Zhao X, Liu J.Immune-enhancing activity of polysaccharides isolated from Atractylodis macrocephalae Koidz.Carbohydr Polym. 2015 Aug 1;126:91-6. doi: 10.1016/j.carbpol.2015.03.034. Epub 2015 Mar 26.PMID: 25933527
79.Wei R, Ma X, Wang G, Guo H, Liu J, Fan L, Cheng Z.Synergistic inhibition of avian leukosis virus subgroup J replication by miRNA-embedded siRNA interference of double-target.Virol J. 2015 Mar 21;12:45. doi: 10.1186/s12985-015-0277-5.PMID: 25889403
80.Fan WT, Zhao XN, Cheng J, Liu YH, Liu JZ.Oxidative stress and hepatocellular injury induced by oral administration of Cr(3+) in chicken.J Biochem Mol Toxicol. 2015 Jun;29(6):280-7. doi: 10.1002/jbt.21697. Epub 2015 Mar 20.PMID: 25800437
81.Liu M, Liu Y, Cheng Z, Liu J, Chai T.Effects of chromic chloride on chick embryo fibroblast viability.Toxicol Rep. 2015 Mar 23;2:555-562. doi: 10.1016/j.toxrep.2015.03.007. eCollection 2015.PMID: 28962390
82.Zhang D, Li H, Zhang Z, Sun S, Cheng Z, Liu J, Zhao P, Ren Q, Guo H.Antibody responses induced by recombinant ALV-A gp85 protein vaccine combining with CpG-ODN adjuvant in breeder hens and the protection for their offspring against early infection.Antiviral Res. 2015 Apr;116:20-6. doi: 10.1016/j.antiviral.2015.01.007. Epub 2015 Jan 28.PMID: 25637708
83.Liu Y, Ma T, Liu J, Zhao X, Cheng Z, Guo H, Xu R, Wang S.Circulating type 1 vaccine-derived poliovirus may evolve under the pressure of adenosine deaminases acting on RNA.J Matern Fetal Neonatal Med. 2015;28(17):2096-9. doi: 10.3109/14767058.2014.979147. Epub 2014 Nov 14.PMID: 25330844
84.Liu Y, Ma T, Liu J, Zhao X, Cheng Z, Guo H, Wang S, Xu R.Bioinformatics analysis and genetic diversity of the poliovirus.J Med Microbiol. 2014 Dec;63(Pt 12):1724-1731. doi: 10.1099/jmm.0.081992-0. Epub 2014 Sep 26.PMID: 25261065
85.Yang D, Zhang Q, Zhang L, Dong H, Jing Z, Li Z, Liu J.Prevalence and risk factors of Giardia doudenalis in dogs from China.Int J Environ Health Res. 2015;25(2):207-13. doi: 10.1080/09603123.2014.915021. Epub 2014 May 12.PMID: 24814763
86.Zhang L, Cai D, Zhao X, Cheng Z, Guo H, Qi C, Liu J, Xu R, Zhao P, Cui Z.Liposomes containing recombinant gp85 protein vaccine against ALV-J in chickens.Vaccine. 2014 May 1;32(21):2452-6. doi: 10.1016/j.vaccine.2014.02.091. Epub 2014 Mar 10.PMID: 24625339
87.Meng K, Sun W, Zhao P, Zhang L, Cai D, Cheng Z, Guo H, Liu J, Yang D,WangS,ChaiT.Development of colloidal gold-based immunochromatographic assay for rapid detection of Mycoplasma suis in porcine plasma.Biosens Bioelectron. 2014 May 15;55:396-9. doi: 10.1016/j.bios.2013.12.048. Epub 2013 Dec 31.PMID: 24434494
88.Wang J, Yang X, Wang Y, Jing Z, Meng K, Liu J, Guo H, Xu R, Cheng Z.Genetic diversity and phylogenetic analysis of Tams1 of Theileria annulata isolates from three continents between 2000 and 2012.Cent Eur J Immunol. 2014;39(4):476-84. doi: 10.5114/ceji.2014.47732. Epub 2014 Dec 15.PMID: 26155166
89.Cai L, Shen Y, Wang G, Guo H, Liu J, Cheng Z.Identification of two novel multiple recombinant avian leukosis viruses in two different lines of layer chicken.J Gen Virol. 2013 Oct;94(Pt 10):2278-2286. doi: 10.1099/vir.0.054239-0. Epub 2013 Jul 24.PMID: 23884361
90.Dou W, Li H, Cheng Z, Zhao P, Liu J, Cui Z, Liu H, Jing W, Guo H.Maternal antibody induced by recombinant gp85 protein vaccine adjuvanted with CpG-ODN protects against ALV-J early infection in chickens.Vaccine. 2013 Dec 9;31(51):6144-9. doi: 10.1016/j.vaccine.2013.06.058. Epub 2013 Jul 2.PMID: 23831319
91.Zhou C, Shi Y, Li J, Zhang W, Wang Y, Liu Y, Liu J.The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice.Pak J Pharm Sci. 2013 Jul;26(4):761-5.PMID: 23811455
92.Zhang L, Wang Y, Cai D, He G, Cheng Z, Liu J, Meng K, Yang D, Wang S.Detection of Anaplasma marginale in Hyalomma asiaticum ticks by PCR assay.Parasitol Res. 2013 Jul;112(7):2697-702. doi: 10.1007/s00436-013-3437-9. Epub 2013 May 2.PMID: 23636309
93.Wang G, Wang Y, Yu L, Jiang Y, Liu J, Cheng Z. New pathogenetic characters of reticuloendotheliosis virus isolated from Chinese partridge in specific-pathogen-free chickens.Microb Pathog. 2012 Aug;53(2):57-63. doi: 10.1016/j.micpath.2012.04.001. Epub 2012 May 3.PMID: 22579709
94.Development and evaluation of enzyme-linked immunosorbent assay based on recombinant inorganic pyrophosphatase gene antigen for the detection of Mycoplasma suis antibodies.Liu J, Zhou D, Cheng Z, Wang Z, Wang L, Wang S, Yang D, Chai T.Res Vet Sci. 2012 Aug;93(1):48-50. doi: 10.1016/j.rvsc.2011.08.016. Epub 2011 Sep 22.PMID: 21940024
95.Wang F, Wang X, Chen H, Liu J, Cheng Z.The critical time of avian leukosis virus subgroup J-mediated immunosuppression during early stage infection in specific pathogen-free chickens.J Vet Sci. 2011 Sep;12(3):235-41. doi: 10.4142/jvs.2011.12.3.235.PMID: 21897096
96.Liu Y, He G, Cheng Z, Qi Y, Liu J, Zhang H, Liu G, Shi D, Yang D, Wang S, Wang Z.Seroprevalence of Toxoplasma gondii in dogs in Shandong, Henan, and Heilongjiang Provinces, and in the Xinjiang Uygur Autonomous Region, People's Republic of China.J Parasitol. 2012 Feb;98(1):211-2. doi: 10.1645/GE-2892.1. Epub 2011 Aug 22.PMID: 21859330
97.Qi C, Zhou D, Liu J, Cheng Z, Zhang L, Wang L, Wang Z, Yang D, Wang S, Chai T. Detection of Babesia divergens using molecular methods in anemic patients in Shandong Province, China.Parasitol Res. 2011 Jul;109(1):241-5. doi: 10.1007/s00436-011-2382-8. Epub 2011 Apr 19.PMID: 21503639
98. Liu J, Cheng Z, Zhou D, Zhang L, Yan Z, Wang Z, Yang D, Liu Y, Chai T.Synthesis, cloning, and expression of Mycoplasma suis inorganic pyrophosphatase gene using PCR-based accurate synthesis and overlap-extension PCR, and its immunogenicity analysis.Res Vet Sci. 2011 Dec;91(3):e100-2. doi: 10.1016/j.rvsc.2011.02.009. Epub 2011 Mar 22.PMID: 21429540
99.Cheng Z, Liu J, Cui Z, Zhang L.Tumors associated with avian leukosis virus subgroup J in layer hens during 2007 to 2009 in China.J Vet Med Sci. 2010 Aug;72(8):1027-33. doi: 10.1292/jvms.09-0564. Epub 2010 May 12.PMID: 20467208
100. Wang L, Wang Z, Liu J.Protective effect of N-acetylcysteine on experimental chronic lead nephrotoxicity in immature female rats.Hum Exp Toxicol. 2010 Jul;29(7):581-91. doi: 10.1177/0960327109357270. Epub 2010 Jan 22.PMID: 20097726
101.Duan H, Chai T, Liu J, Zhang X, Qi C, Gao J, Wang Y, Cai Y, Miao Z, Yao M, Schlenker G.Source identification of airborne Escherichia coli of swine house surroundings using ERIC-PCR and REP-PCR.Environ Res. 2009 Jul;109(5):511-7. doi: 10.1016/j.envres.2009.02.014. Epub 2009 Apr 5.PMID: 19349045
102.Chen TT, Qi C, Guo H, Cheng Z, Zhou D, Liu H, Liu J.The effects of Fu Zi on changes in the body heat of dogs.J Acupunct Meridian Stud. 2009 Mar;2(1):71-4. doi: 10.1016/S2005-2901(09)60018-2. Epub 2009 Apr 7.PMID: 20633477
103.Yan Z, Liu J, Chen T, Cheng Z, Guo H, Wang Z, Wang Y.Treatment of Mycoplasma wenyonii infection in cows with imidocarb dipropionate injection-acupuncture.J Acupunct Meridian Stud. 2008 Dec;1(2):143-8. doi: 10.1016/S2005-2901(09)60035-2.PMID: 20633467
104.Wang Y, Wang ZY, Liu JZ.[Study on the spread approach in eperythrozoonosis of dairy cow].Zhonghua Liu Xing Bing Xue Za Zhi. 2007 Mar;28(3):311-2.PMID: 17649674 Chinese. No abstract available.
105.Liu J, Lee YT, Lee SE, Lee JY, Kim DH. Anti-emetic effect of oculo-acupuncture on dogs with xylazine induced vomiting.Am J Chin Med. 2007;35(3):447-53. doi: 10.1142/S0192415X07004965.PMID: 17597503
106. Liu J, Song KH, You MJ, Son DS, Cho SW, Kim DHThe effect of oculo-acupuncture on recovery from ethylene glycol-induced acute renal injury in dogs..Am J Chin Med. 2007;35(2):241-50. doi: 10.1142/S0192415X07004783.PMID: 17436365
107.Liu J, Cho SN, Song KH, Kim DH, Kim MC, Cho SW.The effect of oculo-acupuncture on acute hepatic injury induced by carbon tetrachloride in dogs.Am J Chin Med. 2007;35(1):53-61. doi: 10.1142/S0192415X07004618.PMID: 17265550
108.Dayou Shi, Mingchao Liu, Shining Guo, Shenquan Liao, Mingfei Sun, Jianzhu Liu*, Lin Wang, Zhenyong Wang, Shujing Wang, Dubao Yang and Tongjie Chai. Serological survey of canine leptospirosis in Southern China. Pak. Vet. J. 2012, 32(2): 280-282.
二．图书出版情况
主编 普通高等教育“十四五”规划教材，高等农林院校“十四五”规划教材《动物影像学》（第二版），中国农业大学出版社，2025年1月。
主编 普通高等教育“十四五”规划教材，高等农林院校“十四五”规划教材《特种经济动物疾病防治学》，中国农业大学出版社（第二版），2023年12月。
主编 国家林业和草原局普通高等教育“十三五”规划教材《动物临床诊断学》（第二版），中国林业出版社，2021年1月出版。
主编 科学出版社普通高等教育“十三五”规划教材《特种动物疾病学》，科学出版社，科学出版社，2020年12月出版。
主编 普通高等教育“十二五”规划教材《动物临床诊断学》（第一版），中国林业出版社，2013年7月。
主编 普通高等教育“十三五”规划教材，高等农林院校“十三五”规划教材《动物影像学》（第一版），中国农业大学出版社，2015年10月。
主编 普通高等教育“十二五”规划教材，高等农林院校“十二五”规划教材《特种经济动物疾病防治学》（第一版），中国农业大学出版社，2014年6月。
主译：“十二五”国家重点图书出版计划，世界兽医经典著作译丛《动物血液学彩色图谱》，中国农业出版社，2012年9月出版.
主编《猪病类症鉴别与诊治彩色图谱》，机械工业出版社，2024年11月出版。
主编《鸡病类症鉴别与诊治彩色图》，机械工业出版社，2024年7月出版。
主编《宠物疾病临床诊疗与用药指南》，化学工业出版社，2024年1月出版。
主编《宠蛋鸡福利养殖技术指南》，中国农业出版社，2024年7月出版。
主编《宠物处方药速查》（第二版），中国农业出版社，2014年3月出版。
主编《宠物医师临床急救手册》，（执业兽医师培训教材）中国农业出版社，2014年4月出版。
主编《猪场兽药规范使用手册》，中国农业出版社，2018年12月出版。
主编《中兽医良方治鸡病》，机械工业出版社，2019年7月出版。
主编《猪病鉴别诊断图谱与安全用药》，机械工业出版社，2017年5月出版。
主编《鸭病鉴别诊断图谱与安全用药》，机械工业出版社，2020年6月出版。
主编《宠物医师临床影像手册》，（执业兽医师培训教材）中国农业出版社，2017年9月出版。
主编《养殖场处方药速查》，中国农业出版社，2014年3月出版。
主编《宠物处方药速查》（第一版），中国农业出版社，2014年3月出版。
主编《常见猪病诊治图谱及安全用药》，中国农业出版社，2011年4月出版。
主编《常见鸡病诊治图谱及安全用药》，中国农业出版社，2011年4月出版。
主编《奶牛场技术管理要点和常见疾病防治》，中国农业出版社，2013年1月出版。
主编 高等农林院校合编教材《特种经济动物疾病学》，中国农业出版社，2009年7月出版。
主审高等职业教育农业农村部“十三五”规划教材，“十三五”江苏省高等院校重点教材《小动物影像技术》（第二版），中国农业出版社，2021年8月出版。
副主编《小动物临床输液疗法》，中国农业出版社，2016年4月出版。
副主编《宠物医师临床药物手册》，金盾出版社，2009年出版。
副主编《宠物医师临床检验手册》，金盾出版社，2008年出版。
参编《现代宠物医生手册》（唐兆新主编），化学工业出版社，2022年1月出版。
参编普通高等教育“十一五”规划教材《动物疾病诊断学》，中国农业出版社，2009年出版。
参编普通高等教育“十一五”规划教材《兽医临床诊断学》，中国农业大学出版社，2011年出版。
参编普通高等教育“十一五”规划教材《犬猫疾病学》，中国农业大学出版社，2011年出版。
参编《小动物内科学》（王九峰教授主编），中国农业出版社，2013年12月出版。
参编《家畜内科学》（庞全海教授主编），中国林业出版社（国家“十二五”规划教材），2015年出版。
参编《家畜内科学》（黄克和教授主编），中国农业大学出版社（国家“十三五”规划教材），2020年出版。
参编普通高等教育“十四五”规划教材，高等农林院校“十四五”规划教材，“大国三农”系列规划教材《家畜内科学》（夏兆飞、夏成、王志主编），中国农业大学出版社，2024年6月出版。
参编科学出版社“十三五”普通高等教育研究生规划教材，创新型现代农林院校研究生系列教材《兽医影像诊断学》，科学出版社，2023年8月出版。