姓名 樊瑞锋
职称:副教授
个人简介
樊瑞锋,博士,副教授,硕士研究生导师。兼任中国畜牧兽医学会兽医内科与临床诊疗学分会理事,山东省兽医协会宠物产业兽医分会专家委员会委员,山东省兽医协会 宠物产业兽医分会理事。主要从事动物营养代谢病与中毒病方面的教学与科研工作,擅长宠物与奶牛疾病的诊疗。
主持及参与国家、省部级自然科学基金项目7项;发表SCI期刊收录论文50余篇,入选美国斯坦福大学和爱思唯尔数据库发布的《全球前2%顶尖科学家榜单2024》;副主编《图说鸡病诊治》,参编《奶牛异常症状的鉴别诊断与治疗》,参译《小动物CT与MRI图谱》;兼任Journal of Hazardous Materials、Ecotoxicology and Environmental Safety、Environmental Pollution、International Journal of Biological Macromolecules、Free Radical Biology and Medicine、Biological Trace Element Research等国外杂志审稿专家。
教育经历
2014 – 2017 ,兽医博士 ,兽医专业 ,东北农业大学
2011 – 2014 ,农学硕士 ,临床兽医学专业 ,山东农业大学
2007 – 2011 ,农学学士 ,动物医学专业 ,山东农业大学
工作经历
2017 – 至今 ,副教授 ,山东农业大学
荣誉奖励
1. 2024年,指导本科生获第九届“雄鹰杯”小动物医师技能大赛团体特等奖,并获“优秀辅导老师奖”。
2. 2023年,指导本科生获第八届“雄鹰杯”小动物医师技能大赛团体特等奖,并获“优秀辅导老师奖”。
3. 2024年,参加中国畜牧兽医学会兽医内科与临床诊疗学分会教学研讨会暨第一届青年教师教学比赛,获“最佳课程思政奖”。
4. 2023年,指导硕士研究生获山东省优秀硕士毕业论文。
5. 2023年,在山东省“技能兴鲁”职业技能大赛-第一届执业兽医职业技能竞赛中担任裁判,获“优秀裁判员”荣誉称号。
执教课程
1. 本科生:兽医内科学、兽医毒理学、小动物疾病学、动物医学研究进展
2. 硕士研究生:动物临床疾病诊疗
研究领域
1. 硒与硒蛋白生物学功能研究
2. 重金属、新兴有机毒物毒理与解毒机制研究
3. 小动物临床疾病诊断与治疗
科研项目
1. 山东农业大学引进人才科研启动基金项目,主持,2017年度
2. 山东省自然科学基金博士基金项目,主持,2018年度
5. 中国博士后科学基金面上项目,主持,2020年度
7. 山东省自然科学基金面上项目,主持,2024年度
发表文章
1.Li Y, Cui H, Li D, Fu H Y, Li J Z, Xu W X, Fan R F. Selenium alleviates pancreatic fibrosis in chickens caused by mercuric chloride: Involvement of the MAPK signaling pathway and selenoproteins [J]. Environ Pollut, 2024, 357: 124448.
2.Li Y, Cui H, Xu W X, Fu H Y, Li J Z, Fan R F. Selenium represses microRNA-202-5p/MICU1 aixs to attenuate mercuric chloride-induced kidney ferroptosis [J]. Poult Sci, 2024, 103(8): 103891.
3.Fu H Y, Li Y, Cui H, Li J Z, Xu W X, Wang X, Fan R F. miR-15b-5p promotes HgCl(2)-induced chicken embryo kidney cells ferroptosis by targeting beta-TrCP-mediated ATF4 ubiquitin degradation [J]. Toxicology, 2024, 503: 153742.
4.Li Y, Li L X, Cui H, Xu W X, Fu H Y, Li J Z, Fan R F. Dietary Iron Overload Triggers Hepatic Metabolic Disorders and Inflammation in Laying Hen [J]. Biol Trace Elem Res, 2024.
5.Fan R F, Chen X W, Cui H, Fu H Y, Xu W X, Li J Z, Lin H. Selenoprotein K knockdown induces apoptosis in skeletal muscle satellite cells via calcium dyshomeostasis-mediated endoplasmic reticulum stress [J]. Poult Sci, 2023, 102(11): 103053.
6.Chu J H, Li L X, Gao P C, Chen X W, Wang Z Y, Fan R F. Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy [J]. Free Radic Biol Med, 2022, 188: 35-44.
7.Chen X W, Chu J H, Li L X, Gao P C, Wang Z Y, Fan R F. Protective mechanism of selenium on mercuric chloride-induced testis injury in chicken via p38 MAPK/ATF2/iNOS signaling pathway [J]. Theriogenology, 2022, 187: 188-194.
8.Li L X, Chu J H, Chen X W, Gao P C, Wang Z Y, Liu C, Fan R F. Selenium ameliorates mercuric chloride-induced brain damage through activating BDNF/TrKB/PI3K/AKT and inhibiting NF-kappaB signaling pathways [J]. J Inorg Biochem, 2022, 229: 111716.
9.Chu J H, Yan Y X, Chen X W, Gao P C, Li L X, Fan R F. Aberrant Gene Expression of Selenoproteins in Chicken Spleen Lymphocytes Induced by Mercuric Chloride [J]. Biol Trace Elem Res, 2022, 200(6): 2857-2865.
10.Gao P C, Chu J H, Chen X W, Li L X, Fan R F. Selenium alleviates mercury chloride-induced liver injury by regulating mitochondrial dynamics to inhibit the crosstalk between energy metabolism disorder and NF-kappaB/NLRP3 inflammasome-mediated inflammation [J]. Ecotoxicol Environ Saf, 2021, 228: 113018.
11.Fan R F, Tang K K, Wang Z Y, Wang L. Persistent activation of Nrf2 promotes a vicious cycle of oxidative stress and autophagy inhibition in cadmium-induced kidney injury [J]. Toxicology, 2021, 464: 152999.
12.Fan R F, Liu J X, Yan Y X, Wang L, Wang Z Y. Selenium relieves oxidative stress, inflammation, and apoptosis within spleen of chicken exposed to mercuric chloride [J]. Poult Sci, 2020, 99(11): 5430-5439.
13.Fan R F, Li Z F, Zhang D, Wang Z Y. Involvement of Nrf2 and mitochondrial apoptotic signaling in trehalose protection against cadmium-induced kidney injury [J]. Metallomics, 2020, 12(12): 2098-2107.
14.Qu K C, Li H Q, Tang K K, Wang Z Y, Fan R F. Selenium Mitigates Cadmium-Induced Adverse Effects on Trace Elements and Amino Acids Profiles in Chicken Pectoral Muscles [J]. Biol Trace Elem Res, 2020, 193(1): 234-240.
15.Chu J H, Yan Y X, Gao P C, Chen X W, Fan R F. Response of selenoproteins gene expression profile to mercuric chloride exposure in chicken kidney [J]. Res Vet Sci, 2020, 133: 4-11.
16.Qu K C, Wang Z Y, Tang K K, Zhu Y S, Fan R F. Trehalose suppresses cadmium-activated Nrf2 signaling pathway to protect against spleen injury [J]. Ecotoxicol Environ Saf, 2019, 181: 224-230.
17.Tang K K, Liu X Y, Wang Z Y, Qu K C, Fan R F. Trehalose alleviates cadmium-induced brain damage by ameliorating oxidative stress, autophagy inhibition, and apoptosis [J]. Metallomics, 2019, 11(12): 2043-2051.
18.Fan R F, Cao C Y, Chen M H, Shi Q X, Xu S W. Gga-let-7f-3p promotes apoptosis in selenium deficiency-induced skeletal muscle by targeting selenoprotein K [J]. Metallomics, 2018, 10(7): 941-952.
19.李玖芝, 付红玉, 许琬雪, 陈雪微, 李玥, 崔晗, 樊瑞锋. 微(纳米)塑料单独及联合重金属暴露所致动物毒性研究进展 [J]. 中国兽医学报, 2024, 44(04): 863-870.
20.付红玉, 李玥, 崔晗, 李玖芝, 许琬雪, 王曦, 樊瑞锋. 长链酯酰辅酶A合成酶4介导铁死亡的发生机制 [J]. 畜牧兽医学报, 2024, 55(09): 3792-3801.